Non-Invasive Prenatal Testing (NIPT)
NIPT Overview
Non-invasive prenatal screening can be helpful in learning more about your baby’s health. It can help you to consider all of your options, how to manage your pregnancy and consider if special management or care is needed. Non-invasive prenatal screening is safe and usually involves just a simple blood test. Your results are usually available about 2 weeks after the test. We advise all parents-to-be to learn about prenatal screening before undertaking any test and it is vital that your results are properly communicated and explained.
Our NIPT Panorama Test from Natera includes:
The opportunity to discuss prenatal screening before you undertake the test with an experienced Midwife with extensive fetal medicine experience
Fetal gender (optional)
An early viability or Growth scan (scan selection depends on your stage in pregnancy)
The opportunity to discuss your results with an experienced Midwife
Information about your options and support with your choices
The Panorama Test from Natera
Panorama is a non-invasive DNA screening test that can give you important information about your pregnancy, from as early as nine weeks into pregnancy. With a simple blood test, you can find out the likelihood of your baby having a condition such as Down Syndrome or Edwards Syndrome. If you choose, you can also find out the gender of your baby. The test is available and validated for single, twin, egg donor and surrogate pregnancies.
Why Choose Panorama?
Panorama has been the test of choice of more than 2 million women around the world, from over 80 countries. It has some exclusive features:
The only NIPT to differentiate between mother and baby’s DNA for the conditions screened
Detection of Triploidy and vanishing twin
Detection of Zygosity
Detection of Maternal X mosaicism
In twin pregnancies, fetal fraction and sex for each twin
Targets over 13,000 SNPs (single nucleotide polymorph) to evaluate the 1% of the DNA that makes us different from each other.
Is Panorama right for me?
According to the International Society for Prenatal Diagnosis (ISPD), non-invasive prenatal testing is appropriate as a primary screening test for pregnant women of all ages. Down Syndrome and certain other chromosomal conditions occur more frequently in babies born to mothers over 35 years old. Other conditions for which Panorama screens – such as microdeletion syndromes – occur with the same frequency in babies, regardless of the mother’s age. See below for a list of conditions that the Panorama Test screens for.
Currently, Panorama cannot be used in the following types of pregnancies:
Multiple gestation pregnancies with 3 or more fetuses
Pregnant women who are bone marrow transplant recipients
What Panorama Screens For
Panorama is the only non-invasive prenatal screening test that distinguishes between fetal and maternal cell-free DNA thanks to SNP-based sequencing and Natera’s proprietary algorithm. Using advanced bioinformatics techniques, Panorama screens for a broad panel of chromosomal conditions, including:
Chromosome Conditions
Trisomy 21 (Down syndrome)
Trisomy 18 (Edwards syndrome)
Trisomy 13 (Patau syndrome)
Triploidy
Sex Chromosome Conditions
Monosomy X (Turner syndrome)
Klinefelter syndrome
Triple X syndrome
Other sex chromosome conditions reported if suspected
Microdeletions
22q deletion syndrome
1p36 deletion syndrome
Prader Willi syndrome
Angelman syndrome
Cri-du-chat syndrome
In Twin Pregnancies
Non-identical or fraternal twins
Trisomy 21 (Down syndrome)
Trisomy 18 (Edwards syndrome)
Trisomy 13 (Patau syndrome)
Gender of each twin (optional)
Zygosity (to see if twins are identical)
Individual fetal fraction for non-identical twins
If our screening finds that your twins are identical, Panorama can additionally screen for:
Monosomy X (Turner syndrome)
Sex chromosome trisomies
22q11.2 deletion syndrome (optional)
Egg Donor or Surrogate Pregnancies
Trisomy 21 (Down syndrome)
Trisomy 18 (Edwards syndrome)
Trisomy 13 (Patau syndrome)
Gender (optional)